The Cut May 21, 2026 • 11:00

A Drugstore Secret for Treating Perimenopause and PMDD? - The Cut

By Katie Heaney

A Drugstore Secret for Treating Perimenopause and PMDD? - The Cut

“Women will go to their doctors and say, ‘I take Allegra and Pepcid and my PMDD symptoms go away. It’s like magic.’’’ But does it really work, and why?

Before perimenopause, Angela hiked over 100 miles a month. I was incredibly active, she told me. I moved to the mountains so I could hike, she tells me. Then: Man, oh man, she says with a sigh. Perim… [+8543 chars]

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