Nature.com April 29, 2026 • 22:15

Translation-dependent degradation of cas12 mRNA triggered by an anti-CRISPR - Nature

The anti-CRISPR protein AcrVA2 specifically interrupts Cas12a biogenesis by triggering co-translational mRNA degradation.

<li>Murtazalieva, K., Mu, A., Petrovskaya, A. & Finn, R. D. The growing repertoire of phage anti-defence systems. Trends Microbiol.32, 12121228 (2024).
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Translation-dependent degradation of cas12 mRNA triggered by an anti-CRISPR - Nature

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