Single-nucleosome imaging/tracking and super-resolution three-dimensional structured illumination microscopy within euchromatic regions show that cohesin-mediated loops constrain condensed euchromatic domains. Cohesin loss increases their fluidity without aff…
All experiments complied with relevant ethical regulations. This study used established human cell lines and involved no human participants, human samples or animals; therefore, no human or animal et… [+20654 chars]