Medscape August 30, 2026 • 15:31

Does AF Ablation Work? That’s in Question After SHAM-PVI-AF - Medscape

By John M. Mandrola, MD

Does AF Ablation Work? That’s in Question After SHAM-PVI-AF - Medscape

Two sham-controlled trials seemingly showed a placebo-resistant benefit to ablation for AF, but the larger SHAM-PVI-AF trial calls those results into question.

Dr John Mandrola
Well, well. Isn’t that something? Professor Rolf Wachter presented the surprising null results of the PVI-SHAM-AF trial on the main stage here in Munich at the European Society of C… [+6452 chars]

More from Medscape