Nature.com July 22, 2026 • 21:45

Precise DNA base editing using AlphaFold3-based contact modelling - Nature

Precise DNA base editing using AlphaFold3-based contact modelling - Nature

ContactSeek is an AlphaFold3-driven model that can improve the precision of genome-editing tools.

<li>Anzalone, A. V., Koblan, L. W. &amp; Liu, D. R. Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors. Nat. Biotechnol.38, 824844 (2020).
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