An ATAC-seq-based approach is used to classify acute myeloid leukaemia (AML) into 16 epigenomic subgroups, and provides insight into the role of non-genetic mechanisms in determining pathogenesis, clinical behaviour and drug sensitivity in this disease.
Patients and samples
This study was reviewed and approved by the regional ethics review board in Stockholm (2008/1330-31/2 and 2017/2085-31/2) and the institutional ethics committees of Kyoto Univer… [+35224 chars]
This study was reviewed and approved by the regional ethics review board in Stockholm (2008/1330-31/2 and 2017/2085-31/2) and the institutional ethics committees of Kyoto Univer… [+35224 chars]