Replication stress induces the formation of transient chromatin loops that enclose de novo heterochromatin-enriched stalled replication forks.
Cell culture, treatments and thymidine analogue incorporation
Cell lines and culture
MRC5 SV40-immortalized human fibroblasts and HCT116 human colorectal cancer cells were cultured in a 1:1 mixture… [+59109 chars]
Cell lines and culture
MRC5 SV40-immortalized human fibroblasts and HCT116 human colorectal cancer cells were cultured in a 1:1 mixture… [+59109 chars]