Different RNA modifications elicit different translation elongation rates for in vitro transcribed mRNAs that result in disparate translation outputs and fidelity, as shown here for N4-acetylcytidine versus the industry standard for synthetic mRNAs, N1-methyl…
Ethics
Human peripheral blood was obtained from de-identified healthy donors through the NIH Clinical Center, Department of Transfusion Medicine, Research Blood Donor Program, under a protocol appro… [+42100 chars]
Human peripheral blood was obtained from de-identified healthy donors through the NIH Clinical Center, Department of Transfusion Medicine, Research Blood Donor Program, under a protocol appro… [+42100 chars]